| Clinical Research |
Advancements in the clinical management of disease states almost always originate from basic or clinical research. It is the constant awareness of this relationship which reinforces the importance of ongoing research.
Nutrishare is committed to conducting and evaluating ongoing research related to long-term TPN therapy. Through research, many questions may be answered. Our intent is to utilize research that we do as well as other studies to improve the level of clinical care for consumers. Our goal is to utilize research to provide consumers with the latest advancements in clinical medicine and ultimately result in improving your health and quality of life.
Below, please find a listing of the research that Nutrishare staff members have presented at national and international meetings. It is organized by year, with the scientific meeting and location of that meeting listed along with the title of the presentation and the authors who conducted the research. In addition, chapters in textbooks and papers published in scientific journals that have been written by Nutrishare staff members are also listed. If there are any questions about any of
these items, please don’t hesitate to contact one of the Nutrishare clinical staff at
1-800-HOME TPN.
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| 2008 |
Siepler JK, Lam K, Diamantidis T, Nishikawa RA, Okamoto R.
Abnormalities of bilirubin, alkaline phosphatase, Aspartine aminotransferase, and Alanine aminotransferase in chronic home parenteral nutrition patients: correlation with patient and clinical characteristics.
JPEN.
NR155 |
| |
John K. Siepler, Pharm.D., Tom Diamantidis, Pharm.D.,
Reid A. Nishikawa, Pharm.D., Rod Okamoto, RPh.
Are consumer surveys accurate data collection tools?
A.S.P.E.N. Nutrition Week, Chicago.
NR154 |
| |
John K. Siepler, Pharm.D., Ken Lam RPh, Tom Diamantidis, Pharm.D.,
Reid A. Nishikawa, Pharm.D., Rod Okamoto, RPh.
Are abnormal liver function tests in chronic home parenteral nutrition patients associated with intravenous fat emulsion packaging?
A.S.P.E.N. Nutrition Week, Chicago.
NR153 |
| |
John K. Siepler, Pharm.D., Tom Diamantidis, Pharm.D.,
Reid Nishikawa, Pharm.D., Rod Okamoto, RPh.
Does a change of infusion provider affect the complication rate and perception of health in chronic home parenteral nutrition patients?
A.S.P.E.N. Nutrition Week, Chicago.
NR152 |
| |
Marianne Opilla, RN BSN CNSN, John Siepler, PharmD BCNSP FCCP,
Thomas Diamantidis, PharmD, Rodney Okamoto, RPh,
Reid Nishikawa, PharmD BCNSP FCSHP
Self Administered Alteplase in a Home Total Parenteral Nutrition Population
A.S.P.E.N. Nutrition Week, Chicago.
NR151 |
| 2007 |
Killmeier G, Siepler, JK, Diamantidis T, Okamoto R.
Strategies for reducing aluminum content of TPN.
Nutrition in Clinical Practice
NR149 |
Killmeier G, Siepler, JK, Diamantidis T, Okamoto R.
Analysis of bacterial contamination of home parenteral nutrition solutions after 28 days storage under room temperature and refrigeration.
In Press: Nutrition in Clinical Practice.
NR148 |
| |
Siepler JK, Okamoto R, Diamantidis T, Nishikawa R.
Incidence of complications associated with chronic home parenteral nutrition is higher in patients who have motility disorders
JPEN
NR147 |
| |
Opilla M, Siepler JK, Nishikawa RA, Diamantidis T, Okamoto R, Kirby D.
Reduction of catheter related blood stream infections using ethanol locks in patients receiving home parenteral Nutrition
JPEN
NR146 |
| |
Siepler JK, Opilla M, Nishikawa RA, Diamantidis T, Okamoto R,
Exit site infections are more common in patients with ostomies.
JPEN
NR145 |
| |
Robertson I, Siepler JK, Opilla M, Nishikawa RA, Diamantidis T, Okamoto R.
Do neutral flow needleless catheter connectors have a reduced rate of catheter changes in chronic home parenteral nutrition patients?
JPEN
NR144 |
| |
Siepler JK, Opilla M. Nishikawa RA, Diamantidis T, Okamoto R.
Reduction of catheter related blood stream infections using ethanol locks in patients receiving home parenteral Nutrition
Pharmacotherapy
NR143 |
| |
Nishikawa RA, Siepler JK, , Diamantidis T, Okamoto R
Osteonecrosis of the jaw in home parenteral nutrition patients on intravenous pamidronate.
Pharmacotherapy
NR142 |
| |
Siepler JK, Nishikawa RA, Diamantidis T, Okamoto R.
Use of acid suppression does not affect bone mineral density in chronic home
Parenteral Nutrition patients. Clinical Nutrition
NR141 |
| |
Siepler JK, Nishikawa RA, Diamantidis T, Okamoto R.
Inflammatory bowel disease patients on home parenteral nutrition with metabolic bone disease have a poorer response to intravenous pamidronate.
Clinical Nutrition Week
NR140 |
| 2006 |
Killmeier G, Siepler JK, Diamantidis T, Nishikawa RA, Okamoto R.
Lack of correlation of metabolic bone disease and estimated Al dosage for chronic home parenteral nutrition patients
JPEN 2006;30:S20.
NR139 |
| |
Siepler JK, Killmeier G, Diamantidis T, Nishikawa R, Okamoto R.
Testing of parenteral nutrition solutions: Validation of freedom from microbial contamination after 28 days storage.
Nutr Clin Pract. 2006;21:221.
NR138 |
| |
Siepler JK, Opilla M, Nishikawa RA, Kirby D, Diamantidis T, Okamoto R.
Reduction of catheter related bloodstream infections using ethanol locks in patients receiving chronic home parenteral nutrition.
Clinical Nutrition (in press)
NR137 |
| |
Siepler JK, Nishikawa RA, Diamantidis T, Okamoto R.
Complications are increased in chronic home parenteral nutrition patients with crohn’s disease receiving monoclonal antibody treatment.
Clinical Nutrition (in press)
NR136 |
| |
Nishikawa RA, Siepler JK, Diamantidis T, Sasaki F, Okamoto R.
Osteonecrosis of the Jaw in chronic home parenteral nutrition patients receiving pamidronate.
Clinical Nutrition (in press)
NR135
|
| 2005 |
Siepler, John K; Nishikawa, Reid A; Diamantidis, Tom; Okamoto, Rod
Quality of life in home parenteral nutrition patients
Abstract: Pharmacotherapy, In press
ACCP Spring Research and Education Forum 2005
Myrtle Beach, SC
NR128
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| |
Siepler, John K; Nishikawa, Reid A; Kumpf, Vanessa; Diamantidis, Tom; Petersen, Craig; Okamoto, Rod; Totty, Darren
Thrombocytopenia in chronic home parenteral nutrition patients
Abstract: Nutr Clin Pract 2005; 20:132.
A.S.P.E.N. Clinical Nutrition Week 2005
Orlando, FL
NR130 |
| |
Siepler, John K; Nishikawa, Reid A; Diamantidis, Tom; Petersen, Craig; Okamoto, Rod
Infectious complications in patients receiving home parenteral nutrition are associated with blood glucose control
Abstract: JPEN 2005; 29:S38.
A.S.P.E.N. Nutrition Week 2005
Orlando, FL
NR108 |
| 2004 |
Siepler, John K; Petersen, Craig; Nishikawa, Reid A; Diamantidis, Tom; Okamoto, Rod
Complications in chronic home parenteral nutrition patients is increased in patients whose actual weight is below desired weight
Abstract: Nutrition in Clinical Practice 2004; 19:82
A.S.P.E.N. Nutrition Week 2004:
American Society for Parenteral and Enteral Nutrition
NR111 |
| |
Kumpf, Vanessa; Okamoto, Rod; Diamantidis, Tom
Long-term use of chlorhexidine for skin antisepsis in home parenteral nutrition patients
Abstract: Nutrition in Clinical Practice 2004; 19:73.
A.S.P.E.N. Nutrition Week 2004:
American Society for Parenteral and Enteral Nutrition
NR106 |
| |
Kumpf, Vanessa
Decrease in infectious complications in a pediatric home parenteral nutrition patient: impact of clinical interventions
Abstract: Nutrition in Clinical Practice 2004; 19:83.
A.S.P.E.N. Nutrition Week 2004:
American Society for Parenteral and Enteral Nutrition
NR112 |
| |
Siepler, John K; Nishikawa, Reid A; Diamantidis, Tom; Petersen, Craig; Okamoto, Rod
Infectious complications in patients receiving home parenteral nutrition are associated with blood glucose control
Abstract: Clinical Nutrition 2004; 23:1487
ESPEN 2004
Annual Meeting of the European Society for Parenteral and Enteral Nutrition
NR120 |
| |
Siepler, John K: Nishikawa, Reid A; Siepler, SE; Diamantidis, Tom; Okamoto, Rod
Intravenous pamidronate successfully reverses diminished bone mineral density in Home TPN patients
Abstract: Gastroenterology. 2004 April
Annual Meeting of the American Gastroenterological Association. DDW 2004
NR129 |
| |
Ryder, Marcia; Nishikawa, Reid A; Liu, YL; Kite, P; Engler, M; Leung, J
Efficacy of tetra sodium EDTA: A novel antimicrobial agent superior to ciprofloxacin in Coagulase-negative Staphylococcus and Pseudomonas aeruginosa biofilm bacteria
ICAAC 2004
Washington DC
NR98B |
| |
Ryder, Marcia; Nishikawa, Reid; Liu YL; Engler M; Leung J
Electroporation: Pulsed electrical fields produce rapid reduction of Coagulase-negative Staphylococcus biofilm bacteria when used alone or in combination with antibiotics
ICAAC 2004
Washington DC
NR98C |
| 2003 |
Siepler, John K; Avante, Clare
Quality of life in patients receiving chronic home parenteral nutrition (HPN) is not affected by incidence of HPN associated complications
Abstract: JPEN 2003; 27(1): S32.
A.S.P.E.N. Nutrition Week 2003:
American Society for Parenteral and Enteral Nutrition
NR97 |
| |
Nishikawa, Reid A; Siepler, SE; Siepler, John K; Diamantidis, Tom;
Okamoto, Rod
Intravenous pamidronate improves bone mineral density in home parenteral nutrition patients.
Abstract: Clinical Nutrition. 2003; 22:S88.
ESPEN 2003
Annual Meeting of the European Society for Parenteral and Enteral Nutrition
NR101 |
| |
Siepler, John K; Nishikawa, Reid A; Diamantidis, Tom; Okamoto, Rod
Home parenteral nutrition in patients using specialized home care providers without complications have a higher quality of life than those using a general home care provider.
Abstract: Clinical Nutrition. Aug 2003; 22:S89.
ESPEN, 2003
Annual Meeting of the European Society for Parenteral and Enteral Nutrition
NR96 |
| |
Ryder, Marcia; Nishikawa, Reid A; Liu, YL; Kite, P; Engler, M; Leung, J
Efficacy of tetra sodium EDTA: A novel antimicrobial agent superior to ciprofloxacin in Coagulase-negative Staphylococcus and Pseudomonas aeruginosa biofilm bacteria
American Society of Microbiology (ASM) Conferences,
Biofilms 2003,
Victoria, British Columbia
NR98 |
| |
Ryder, Marcia; Nishikawa, Reid A; Liu, YL; Engler, M; Leung, J
Electroporation: pulsed electrical fields produce rapid reduction of Coagulase-negative Staphylococcus biofilm bacteria when used alone or in combination with antibiotics
American Society of Microbiology (ASM) Conferences,
Biofilms 2003,
Victoria, British Columbia
NR98 |
| 2002 |
Siepler, John K; Okamoto, Rod; Diamantidis, Tom; Nishikawa, Reid A
Quality of life analysis in patients with chronic intestinal pseudobstruction on home parenteral nutrition
Abstract: Clinical Nutrition. October 2002.
ESPEN, 2002
Annual Meeting of the European Society for Parenteral and Enteral Nutrition
NR117 |
| |
Siepler, John K; Totty, Darren E; Okamoto, Rod; Diamantidis, Tom; Nishikawa, Reid A
Reformulated parenteral multivitamins in long-term parenteral nutrition patients: impact on therapeutic anticoagulation
American Society for Health-System Pharmacists (ASHP) Mid-Year Clinical Meeting, 2002.
NR105 |
| |
Hester, Mike L; Okamoto, Rod; Diamantidis, Tom
Efficacy of low dose tPA in occluded catheters in long term TPN patients
American Society for Health-System Pharmacists (ASHP) Mid-Year Clinical Meeting, 2002.
NR100 |
| 2001 |
Nishikawa, Reid A; Siepler, John K; Diamantidis, Tom; Okamoto, Rod
Elevated manganese levels in long-term home parenteral nutrition patients is not predicted by dose
Abstract: JPEN 2001; 25:S7.
American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.) Clinical Congress, 2001.
NR103 |
| |
Siepler, John K; Okamoto, Rod; Diamantidis, Tom; Nishikawa, Reid A; Totty, Darren E; Hester, Michael L
Monthly urokinase (URO) in long-term home TPN (HPN) patients reduces
the incidence of hospital admissions
Abstract: JPEN. 2001; 25:S7.
American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.) Clinical Congress, 2001.
NR109 |
| |
Siepler, John K; Petersen, Craig; Okamoto, Rod; Diamantidis, Tom; Nishikawa, Reid A
Ability of patients with short bowel syndrome (SBS) to wean of home parenteral nutrition (HPN ) after an intestinal rehabilitation program (BRP) is related to remaining bowel length.
Abstract: Clinical Nutrition. Sept 2001
ESPEN, 2001.
Annual Meeting of the European Society for Parenteral and Enteral Nutrition
NR104 |
| 2000 |
Siepler, John K; Nishikawa, Reid A; Diamantidis, Tom; Petersen, Craig; Okamoto, Rod
Pediatric patients on home parenteral nutrition (HPN) wean off hpn (WHPN) easier than adults
Abstract: Clinical Nutrition. Sept 2000.
ESPEN, 2000.
Annual Meeting of the European Society for Parenteral and Enteral Nutrition
NR102 |
| |
Siepler, John K; Nishikawa, Reid A; Diamantidis, Tom; Okamoto, Rod
Attendance at a bowel rehabilitation program is not associated with an increased ability to wean from parenteral nutrition in patients with short bowel syndrome after bowel resection
Abstract: Gastroenterology 2000; 118:A1097.
Annual meeting of the American Gastroenterology Association (DDW), 2000.
NR113 |
| |
Siepler, John K; Nishikawa, Reid A; Diamantidis, Tom; Peterson, Craig; Okamoto, Rod
Relationship of gastrointestinal (GI) anatomy and ability to wean off of
parenteral Nutrition (HPN) in patients with short bowel syndrome (SBS) following multiple bowel resection (MBR)
Abstract: JPEN 2000; 24:S26
A.S.P.E.N. Clinical Congress, 2000
American Society for Parenteral and Enteral Nutrition
NR124 |
| 1999 |
Siepler, John K; Nishikawa, Reid A; Hester, Mike; et al.
Routine urokinase reduces catheter complications in patients on chronic home parenteral nutrition
Abstract: Gastroenterology. April 1999.
Annual meeting of the American Gastroenterology Association (DDW), 1999.
NR118 |
| 1997 |
Siepler, John K; Petersen, Craig; Okamoto, Rod; Diamantidis, Tom; Nishikawa, Reid A
An analysis of home TPN related hospital admissions: comparison of specialized and general home care providers
ASHP Annual Meeting, 1997.
American Society for Health-System Pharmacists
NR99 |
| Textbook Chapters: |
Textbook chapter:
Chessman K; Kumpf, Vanessa;
Assessment of nutrition status and nutrition requirements.
In: Pharmacotherapy: A pathophysiologic approach
DiPiro JT, ed. 6th ed.
Appleton & Lange; publication pending.
NR122 |
| |
Textbook chapter:
Kumpf, Vanessa; Chessman, K.
Enteral Nutrition
In: Pharmacotherapy: A pathophysiologic approach
DiPiro JT, ed 6th ed.
Appleton & Lange; publication pending.
NR121 |
| |
Textbook chapter:
Martindale RG, Shikora SA, Nishikawa, Reid A; Siepler, John K;
The metabolic response to stress and alterations in nutrient metabolism
In: Nutritional considerations in the intensive care unit.
Shakoura, S; Martindale, RG, editors
Kendal-Hunt, Bethesda, MD: 2003; pp 11-21
NR125 |
| |
Textbook chapter:
Kumpf, Vanessa; Gervasio J
Pharmacotherapeutics
In: The science and practice of nutrition support: A case-based core curriculum
Gottschlich M, ed.
A.S.P.E.N., Inc Silver Spring: 2001; pp 287-299.
NR119 |
| |
Textbook chapter:
Seipler, John K and Phinney, SP
TPN in the diabetic patient
In: Nutrition Support: Theory and Therapeutics,
Shakoura S and Blackburn, GL editors Chapman and Hall. New York, NY, 1997, pp 321-335
NR126 |
| Journal Articles: |
Journal article:
Mirtallo J; Canada T; Johnson D; Kumpf, Vanessa; Petersen, Craig; Sacks G; Seres D, Guenter P.
Safe practices for parenteral nutrition.
JPEN 2004; 28(6 suppl): S39-S70.
NR123 |
| |
Journal article:
Kumpf, Vanessa
Update on parenteral iron therapy.
Nutrition in Clinical Practice 2003; 18:318-326.
NR115 |
| |
Journal article:
Siepler, John K; Nishikawa, Reid A; Diamantidis, Tom; Okamoto, Rod
Asymptomatic hypermanganesemia in long-term home parenteral nutrition patients.
Nutrition in Clinical Practice 2003; 18:370-373.
NR116 |
| |
Journal article:
Kumpf, Vanessa
Implementation of safe practices for parenteral nutrition formulations.
Am J Health-Syst Pharm 1999; 56:815-817.
NR107 |
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Journal article:
Kumpf, Vanessa
Current guidelines for the use of parenteral nutrition.
Home Health Care Consultant 1999; 6:20-25.
NR114 |
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