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Clinical Research

Advancements in the clinical management of disease states almost always originate from basic or clinical research. It is the constant awareness of this relationship which reinforces the importance of ongoing research.

Nutrishare is committed to conducting and evaluating ongoing research related to long-term TPN therapy. Through research, many questions may be answered. Our intent is to utilize research that we do as well as other studies to improve the level of clinical care for consumers. Our goal is to utilize research to provide consumers with the latest advancements in clinical medicine and ultimately result in improving your health and quality of life.

Below, please find a listing of the research that Nutrishare staff members have presented at national and international meetings. It is organized by year, with the scientific meeting and location of that meeting listed along with the title of the presentation and the authors who conducted the research. In addition, chapters in textbooks and papers published in scientific journals that have been written by Nutrishare staff members are also listed. If there are any questions about any of these items, please don’t hesitate to contact one of the Nutrishare clinical staff at 1-800-HOME TPN.

 
2005

Siepler, John K; Nishikawa, Reid A; Diamantidis, Tom; Okamoto, Rod
Quality of life in home parenteral nutrition patients
Abstract: Pharmacotherapy, In press
ACCP Spring Research and Education Forum 2005
Myrtle Beach, SC
NR128

 
Siepler, John K; Nishikawa, Reid A; Kumpf, Vanessa; Diamantidis, Tom; Petersen, Craig; Okamoto, Rod; Totty, Darren
Thrombocytopenia in chronic home parenteral nutrition patients
Abstract: Nutr Clin Pract 2005; 20:132.
A.S.P.E.N. Clinical Nutrition Week 2005
Orlando, FL
NR130
 
Siepler, John K; Nishikawa, Reid A; Diamantidis, Tom; Petersen, Craig; Okamoto, Rod
Infectious complications in patients receiving home parenteral nutrition are associated with blood glucose control
Abstract: JPEN 2005; 29:S38.
A.S.P.E.N. Nutrition Week 2005
Orlando, FL
NR108
2004
Siepler, John K; Petersen, Craig; Nishikawa, Reid A; Diamantidis, Tom; Okamoto, Rod
Complications in chronic home parenteral nutrition patients is increased in patients whose actual weight is below desired weight
Abstract: Nutrition in Clinical Practice 2004; 19:82
A.S.P.E.N. Nutrition Week 2004:
American Society for Parenteral and Enteral Nutrition
NR111
 
Kumpf, Vanessa; Okamoto, Rod; Diamantidis, Tom
Long-term use of chlorhexidine for skin antisepsis in home parenteral nutrition patients
Abstract: Nutrition in Clinical Practice 2004; 19:73.
A.S.P.E.N. Nutrition Week 2004:
American Society for Parenteral and Enteral Nutrition
NR106
 
Kumpf, Vanessa
Decrease in infectious complications in a pediatric home parenteral nutrition patient: impact of clinical interventions
Abstract: Nutrition in Clinical Practice 2004; 19:83.
A.S.P.E.N. Nutrition Week 2004:
American Society for Parenteral and Enteral Nutrition
NR112
 
Siepler, John K; Nishikawa, Reid A; Diamantidis, Tom; Petersen, Craig; Okamoto, Rod
Infectious complications in patients receiving home parenteral nutrition are associated with blood glucose control
Abstract: Clinical Nutrition 2004; 23:1487
ESPEN 2004
Annual Meeting of the European Society for Parenteral and Enteral Nutrition
NR120
 

Siepler, John K: Nishikawa, Reid A; Siepler, SE; Diamantidis, Tom; Okamoto, Rod
Intravenous pamidronate successfully reverses diminished bone mineral density in Home TPN patients
Abstract: Gastroenterology. 2004 April
Annual Meeting of the American Gastroenterological Association. DDW 2004
NR129

 
Ryder, Marcia; Nishikawa, Reid A; Liu, YL; Kite, P; Engler, M; Leung, J
Efficacy of tetra sodium EDTA: A novel antimicrobial agent superior to ciprofloxacin in Coagulase-negative Staphylococcus and Pseudomonas aeruginosa biofilm bacteria
ICAAC 2004
Washington DC
NR98B
 
Ryder, Marcia; Nishikawa, Reid; Liu YL; Engler M; Leung J
Electroporation: Pulsed electrical fields produce rapid reduction of Coagulase-negative Staphylococcus biofilm bacteria when used alone or in combination with antibiotics
ICAAC 2004
Washington DC
NR98C
2003
Siepler, John K; Avante, Clare
Quality of life in patients receiving chronic home parenteral nutrition (HPN) is not affected by incidence of HPN associated complications
Abstract: JPEN 2003; 27(1): S32.
A.S.P.E.N. Nutrition Week 2003:
American Society for Parenteral and Enteral Nutrition
NR97
 
Nishikawa, Reid A; Siepler, SE; Siepler, John K; Diamantidis, Tom;
Okamoto, Rod
Intravenous pamidronate improves bone mineral density in home parenteral nutrition patients.
Abstract: Clinical Nutrition. 2003; 22:S88.
ESPEN 2003
Annual Meeting of the European Society for Parenteral and Enteral Nutrition
NR101
 
Siepler, John K; Nishikawa, Reid A; Diamantidis, Tom; Okamoto, Rod
Home parenteral nutrition in patients using specialized home care providers without complications have a higher quality of life than those using a general home care provider.
Abstract: Clinical Nutrition. Aug 2003; 22:S89.
ESPEN, 2003
Annual Meeting of the European Society for Parenteral and Enteral Nutrition
NR96
 
Ryder, Marcia; Nishikawa, Reid A; Liu, YL; Kite, P; Engler, M; Leung, J
Efficacy of tetra sodium EDTA: A novel antimicrobial agent superior to ciprofloxacin in Coagulase-negative Staphylococcus and Pseudomonas aeruginosa biofilm bacteria
American Society of Microbiology (ASM) Conferences,
Biofilms 2003,
Victoria, British Columbia
NR98
 
Ryder, Marcia; Nishikawa, Reid A; Liu, YL; Engler, M; Leung, J
Electroporation: pulsed electrical fields produce rapid reduction of Coagulase-negative Staphylococcus biofilm bacteria when used alone or in combination with antibiotics
American Society of Microbiology (ASM) Conferences,
Biofilms 2003,
Victoria, British Columbia
NR98
2002
Siepler, John K; Okamoto, Rod; Diamantidis, Tom; Nishikawa, Reid A
Quality of life analysis in patients with chronic intestinal pseudobstruction on home parenteral nutrition
Abstract: Clinical Nutrition. October 2002.
ESPEN, 2002
Annual Meeting of the European Society for Parenteral and Enteral Nutrition
NR117
 
Siepler, John K; Totty, Darren E; Okamoto, Rod; Diamantidis, Tom; Nishikawa, Reid A
Reformulated parenteral multivitamins in long-term parenteral nutrition patients: impact on therapeutic anticoagulation
American Society for Health-System Pharmacists (ASHP) Mid-Year Clinical Meeting, 2002.
NR105
 
Hester, Mike L; Okamoto, Rod; Diamantidis, Tom
Efficacy of low dose tPA in occluded catheters in long term TPN patients
American Society for Health-System Pharmacists (ASHP) Mid-Year Clinical Meeting, 2002.
NR100
2001
Nishikawa, Reid A; Siepler, John K; Diamantidis, Tom; Okamoto, Rod
Elevated manganese levels in long-term home parenteral nutrition patients is not predicted by dose
Abstract: JPEN 2001; 25:S7.
American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.) Clinical Congress, 2001.
NR103
 
Siepler, John K; Okamoto, Rod; Diamantidis, Tom; Nishikawa, Reid A; Totty, Darren E; Hester, Michael L
Monthly urokinase (URO) in long-term home TPN (HPN) patients reduces the incidence of hospital admissions
Abstract: JPEN. 2001; 25:S7.
American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.) Clinical Congress, 2001.
NR109
 
Siepler, John K; Petersen, Craig; Okamoto, Rod; Diamantidis, Tom; Nishikawa, Reid A
Ability of patients with short bowel syndrome (SBS) to wean of home parenteral nutrition (HPN ) after an intestinal rehabilitation program (BRP) is related to remaining bowel length.
Abstract: Clinical Nutrition. Sept 2001
ESPEN, 2001.
Annual Meeting of the European Society for Parenteral and Enteral Nutrition
NR104
2000
Siepler, John K; Nishikawa, Reid A; Diamantidis, Tom; Petersen, Craig; Okamoto, Rod
Pediatric patients on home parenteral nutrition (HPN) wean off hpn (WHPN) easier than adults
Abstract: Clinical Nutrition. Sept 2000.
ESPEN, 2000.
Annual Meeting of the European Society for Parenteral and Enteral Nutrition
NR102
 
Siepler, John K; Nishikawa, Reid A; Diamantidis, Tom; Okamoto, Rod
Attendance at a bowel rehabilitation program is not associated with an increased ability to wean from parenteral nutrition in patients with short bowel syndrome after bowel resection
Abstract: Gastroenterology 2000; 118:A1097.
Annual meeting of the American Gastroenterology Association (DDW), 2000.
NR113
 
Siepler, John K; Nishikawa, Reid A; Diamantidis, Tom; Peterson, Craig; Okamoto, Rod
Relationship of gastrointestinal (GI) anatomy and ability to wean off of parenteral Nutrition (HPN) in patients with short bowel syndrome (SBS) following multiple bowel resection (MBR)
Abstract: JPEN 2000; 24:S26
A.S.P.E.N. Clinical Congress, 2000
American Society for Parenteral and Enteral Nutrition
NR124
1999
Siepler, John K; Nishikawa, Reid A; Hester, Mike; et al.
Routine urokinase reduces catheter complications in patients on chronic home parenteral nutrition
Abstract: Gastroenterology. April 1999.
Annual meeting of the American Gastroenterology Association (DDW), 1999.
NR118
1997
Siepler, John K; Petersen, Craig; Okamoto, Rod; Diamantidis, Tom; Nishikawa, Reid A
An analysis of home TPN related hospital admissions: comparison of specialized and general home care providers
ASHP Annual Meeting, 1997.
American Society for Health-System Pharmacists
NR99
Textbook Chapters:
Textbook chapter:
Chessman K; Kumpf, Vanessa;
Assessment of nutrition status and nutrition requirements.
In: Pharmacotherapy: A pathophysiologic approach

DiPiro JT, ed. 6th ed.
Appleton & Lange; publication pending.
NR122
 
Textbook chapter:
Kumpf, Vanessa; Chessman, K.
Enteral Nutrition
In: Pharmacotherapy: A pathophysiologic approach

DiPiro JT, ed 6th ed.
Appleton & Lange; publication pending.
NR121
 
Textbook chapter:
Martindale RG, Shikora SA, Nishikawa, Reid A; Siepler, John K;
The metabolic response to stress and alterations in nutrient metabolism
In: Nutritional considerations in the intensive care unit.

Shakoura, S; Martindale, RG, editors
Kendal-Hunt, Bethesda, MD: 2003; pp 11-21
NR125
 
Textbook chapter:
Kumpf, Vanessa; Gervasio J
Pharmacotherapeutics
In: The science and practice of nutrition support: A case-based core curriculum

Gottschlich M, ed.
A.S.P.E.N., Inc Silver Spring: 2001; pp 287-299.
NR119
 
Textbook chapter:
Seipler, John K and Phinney, SP
TPN in the diabetic patient
In: Nutrition Support: Theory and Therapeutics,

Shakoura S and Blackburn, GL editors Chapman and Hall. New York, NY, 1997, pp 321-335
NR126
Journal Articles:
Journal article:
Mirtallo J; Canada T; Johnson D; Kumpf, Vanessa; Petersen, Craig; Sacks G; Seres D, Guenter P.
Safe practices for parenteral nutrition.
JPEN 2004; 28(6 suppl): S39-S70.
NR123
 
Journal article:
Kumpf, Vanessa
Update on parenteral iron therapy.
Nutrition in Clinical Practice 2003; 18:318-326.
NR115
 
Journal article:
Siepler, John K; Nishikawa, Reid A; Diamantidis, Tom; Okamoto, Rod
Asymptomatic hypermanganesemia in long-term home parenteral nutrition patients.
Nutrition in Clinical Practice 2003; 18:370-373.
NR116
 
Journal article:
Kumpf, Vanessa
Implementation of safe practices for parenteral nutrition formulations.
Am J Health-Syst Pharm 1999; 56:815-817.
NR107
 
Journal article:
Kumpf, Vanessa
Current guidelines for the use of parenteral nutrition.
Home Health Care Consultant 1999; 6:20-25.
NR114
 
 
 
 
 
 
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